JPH039919B2 - - Google Patents

Info

Publication number
JPH039919B2
JPH039919B2 JP57101462A JP10146282A JPH039919B2 JP H039919 B2 JPH039919 B2 JP H039919B2 JP 57101462 A JP57101462 A JP 57101462A JP 10146282 A JP10146282 A JP 10146282A JP H039919 B2 JPH039919 B2 JP H039919B2
Authority
JP
Japan
Prior art keywords
group
meoh
formula
chloroform
acetone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP57101462A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58219197A (ja
Inventor
Rokuro Okamoto
Koki Kyoshima
Tomoyuki Ishikura
Kuniaki Tatsuta
Tomio Takeuchi
Hamao Umezawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MERUSHAN KK
Original Assignee
MERUSHAN KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MERUSHAN KK filed Critical MERUSHAN KK
Priority to JP57101462A priority Critical patent/JPS58219197A/ja
Priority to US06/502,480 priority patent/US4463171A/en
Priority to EP83105887A priority patent/EP0096900B1/en
Priority to DE8383105887T priority patent/DE3369996D1/de
Publication of JPS58219197A publication Critical patent/JPS58219197A/ja
Publication of JPH039919B2 publication Critical patent/JPH039919B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP57101462A 1982-06-15 1982-06-15 マクロライド系抗生物質の誘導体 Granted JPS58219197A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP57101462A JPS58219197A (ja) 1982-06-15 1982-06-15 マクロライド系抗生物質の誘導体
US06/502,480 US4463171A (en) 1982-06-15 1983-06-09 Derivatives of macrolide antibiotics
EP83105887A EP0096900B1 (en) 1982-06-15 1983-06-15 Derivatives of macrolide antibiotics
DE8383105887T DE3369996D1 (en) 1982-06-15 1983-06-15 Derivatives of macrolide antibiotics

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57101462A JPS58219197A (ja) 1982-06-15 1982-06-15 マクロライド系抗生物質の誘導体

Publications (2)

Publication Number Publication Date
JPS58219197A JPS58219197A (ja) 1983-12-20
JPH039919B2 true JPH039919B2 (en]) 1991-02-12

Family

ID=14301366

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57101462A Granted JPS58219197A (ja) 1982-06-15 1982-06-15 マクロライド系抗生物質の誘導体

Country Status (4)

Country Link
US (1) US4463171A (en])
EP (1) EP0096900B1 (en])
JP (1) JPS58219197A (en])
DE (1) DE3369996D1 (en])

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4436729A (en) * 1982-06-30 1984-03-13 Schering Corporation 23-Demycinosyltylosin compounds, pharmaceutical compositions and method of use
US4452784A (en) * 1982-07-19 1984-06-05 Eli Lilly And Company C-23-Modified derivatives of DMT
DE3444006A1 (de) * 1983-11-30 1985-06-05 Toyo Jozo K.K., Tagata, Shizuoka 14-de(hydroxymethyl)-mycaminosyltylonolid-derivate
US4604380A (en) * 1985-01-18 1986-08-05 Eli Lilly And Company C-23-substituted mycaminosyltylonolide compounds, pharmaceutical compositions and methods of use
US4851518A (en) * 1985-12-23 1989-07-25 Schering Corporation Di and tri-O-acetyl-"O-iso-valeryl-23-O-demycinosyl tylosins, hydrazone derivatives thereof and processes for their preparation
JP5521320B2 (ja) * 2008-12-10 2014-06-11 日本精工株式会社 潤滑剤組成物及び転動装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH630391A5 (en) * 1975-02-28 1982-06-15 Scherico Ltd Process for preparing derivatives of rosaramicin
JPS6016960B2 (ja) * 1978-09-20 1985-04-30 メルシャン株式会社 マクロライド系抗生物質ｎ−１及びその製造法
ZA813578B (en) * 1980-06-12 1983-01-26 Lilly Co Eli Macrolide antibiotics
US4321361A (en) * 1980-06-12 1982-03-23 Eli Lilly And Company Demycinosyltylosin and process for its production
US4279896A (en) * 1980-06-23 1981-07-21 Schering Corporation Novel 20-imino macrolide antibacterial agents
US4438109A (en) * 1980-07-25 1984-03-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Tylosin derivatives
US4341770A (en) * 1981-04-20 1982-07-27 Eli Lilly And Company Method of controlling ureaplasma infections
AU551142B2 (en) * 1981-07-09 1986-04-17 Zaidan Hojin Biseibutsu Kagaku Kenkyukai Tylosin derivatives
CA1185968A (en) * 1981-12-14 1985-04-23 Herbert A. Kirst Method of preparing 23-monoesters of omt and dmt
US4396613A (en) * 1981-12-14 1983-08-02 Eli Lilly And Company 23-Ester derivatives of DMT and method of using same
IL65119A0 (en) * 1982-02-26 1982-04-30 Arda Plast B M Packing trays
US4452784A (en) * 1982-07-19 1984-06-05 Eli Lilly And Company C-23-Modified derivatives of DMT

Also Published As

Publication number Publication date
DE3369996D1 (en) 1987-04-09
JPS58219197A (ja) 1983-12-20
US4463171A (en) 1984-07-31
EP0096900A1 (en) 1983-12-28
EP0096900B1 (en) 1987-03-04

Similar Documents

Publication Publication Date Title
DK172636B1 (en) 6-o-methylerythromycin a derivative
KR100244729B1 (ko) 5-0-데소사미닐에리쓰로노라이드a유도체
USRE39836E1 (en) Macrolide antinfective agents
KR850000965B1 (ko) 4"-에피 에리스로마이신 a 및 그의 유도체의 제조방법
IE841665L (en) Homoerythromycin a derivatives. sterile surgical needle having dark non-reflective surface.
JPH039919B2 (en])
US5519122A (en) 16-membered macrolide derivatives and process for producing the same
JPS6360031B2 (en])
US6794366B2 (en) Macrolide antiinfective agents
US4933439A (en) Tylosin derivatives and processes for producing the same
CA1151160A (en) Erythromycylamine 11,12-carbonate and derivatives thereof
JPH0550519B2 (en])
JPS6152839B2 (en])
JPH0567156B2 (en])
JPH0529038B2 (en])
FR2520366A1 (fr) Derives de 23-o-acyl-23-demycinosyldesmycosine
JP3074098B2 (ja) 新規１６員環マクロリド誘導体
JP3078965B2 (ja) 新規１６員環マクロリド誘導体
US4064143A (en) Oleandomycin derivatives
KR820001220B1 (ko) 반합성 4"-에리트로마이신 a 유도체의 제조방법
CN1197075A (zh) 从红霉素衍生的新的断大环内酯类及其制备方法
US4876245A (en) Fluorine-containing macrolide compounds and their use
JPH0510356B2 (en])
KR820001219B1 (ko) 반합성 4"-에리트로마이신 a 유도체의 제조방법
KR100834711B1 (ko) 엔-아실-5'-데옥시-5-플루오로시티딘 유도체의 제조 방법